Dr. Ghorbani's extensive research into alternative pain relief treatments began during his medical education at Tufts. While at Tufts, he co-authored numerous groundbreaking scientific papers about inflammation that were published in respected medical journals such as the New England Journal of Medicine and the European Journal of Immunology, among others.
His quest to find a natural pain management alternative sparked a discovery that lead outside the traditional pain management box to the proprietary formulation of 7 of the world's most potent natural pain relievers: turmeric, willow bark, ginger, holy basil, rosemary extract, alpha lipoic acids and boswellia extract.
Dr. Ghorbani chose each centuries-old ingredient not only because of its proven singular effectiveness for treating different types of pain, but also because he understood that each ingredient served as a catalyst to the other ingredients to boost the effectiveness of the formulation as a whole.
The resulting US patent-pending Noxicare™ formula is unique for many important reasons: it is fast-acting, long-lasting, highly effective, natural, no known side effects, and it can be used in conjunction with a traditional pain management program. Importantly, with Noxicare™, Dr. Ghorbani realized his goal of creating a safe first-line pain management remedy that is accessible to everyone.
90% of patients using Noxicare™ had reduced pain; 60% reduced pain by half.
Background and Purpose: Patients with muscle and joint dysfunction often experience waxing and waning episodes of inflammation. The purpose of this study was to evaluate the efficacy of Noxicare™ in assisting patients with management of these episodes.
Study Description: 30 patients with a variety of musculoskeletal diagnoses were chosen for the study. The diagnoses included: cervical strain, lumbar strain, knee sprain, shoulder sprain, knee OA, hand OA and tendinitis of the knee, elbow and shoulder. All patients received an initial week of therapy without the use of Noxicare™. Pain and irritation was evaluated at the start of treatment and at the end of the initial week using the VAS. Following the initial week of therapy, no changes were made in the plan of care except for the addition of Noxicare™ which was used during each treatment for a period of 2 weeks. Each patient was also given a tube for use at home. Patients were instructed to apply liberally 2- 3 times per day for a period of 2 weeks. Return demonstration was required by each patient to ensure proper application. Pain assessments were performed at weekly using the VAS. The results are at right.
Results: 60% of the patients had a 50% or more reduction in pain during the 2 week trial. 90% of the patients had some reduction in pain during the two week trial. One patient returned the cream and refused to continue using and 3 patients had no change.
Conclusion: The study demonstrates that Noxicare™ can be a useful for reducing musculoskeletal pain and inflammation.
In January 2010, The Benchmarking Company (TBC) was hired by Truceuticals® Inc. to conduct a case study of Noxicare™, a natural topical pain-relief cream created to alleviate acute and chronic pain associated with: joint and muscle inflammation. The study probed the level of pain experienced by participants through a variety of questions designed to capture as much information as possible on the type of pain, location, and severity. After using the product for 7 days, participants were then asked to rate their pain experience.
Types of Pain Studied
Out of the three types of pain studied — chronic, muscular or nerve — 68% of the participants in the study described their pain as muscular — those aches and pains associated with everyday over-exertion, athletic pain such as from a sporting injury, or even pain associated with medical conditions such as fibromyalgia or cancer treatments. Chronic pain, which might include side effects like burning or swelling of ligaments, accounted for 48% of respondents and nerve pain — throbbing or stinging pain often described as 'pins and needles' accounted for 20%.
7 Day Results
To set a benchmark for pain levels, at the start of the study, TBC asked all participants to rate their level of pain on a scale of 0 -10 (with 0 being 'no pain', and 10 being 'unbearable pain'). At this time, just over half rated their pain as 'moderate to severe'; pain that was discomforting and distressing, and significantly impacted day-to-day activities. After just 7 days of using Noxicare™, an astounding 72% of participants overwhelmingly agreed that their level of pain shrank dramatically from 'moderate to severe', to 'little to mild', while 48% reported they had very little to no pain. A reduction in pain wasn't the only thing participants raved about: 60% also noticed less inflammation and swelling.
After 7 days of using Noxicare™
Testimonials from Clinical Results
We have begun a research project to evaluate the skin damage (irritation) induced by Noxicare™ cream and other commonly used "counter irritant products." Normal Health Volunteers will be enrolled to determine what changes are noticed.
We have started developing a protocol to evaluate the comparative skin damage (irritation) induced by several other topical analgesic products and Noxicare™ in addition to the question of efficacy for pain alleviation and control.
Our goal is to quantify the safety and efficacy differences between groups over a one month treatment period. It is our intent to study patients with diabetic neuropathy related foot pain. The enrollment will insure the subjects are currently under the care of physicians directly responsible for their diabetes and/or neuropathy.
This protocol will be finalized after the completion and analysis of the Normal Healthy Volunteer Study listed above – expected to be in January/February 2013 with a start date of March 2013.
We are developing a process by which we can evaluate the safety issues found with all the ingredients found in topical and oral analgesic products.
Specifically we are going to engage a research company to do a literature search to identify the potential safety issues of our most frequently used competitors. This same literature search will be done for Noxicare™ cream and capsules (including a search which looks at information for each ingredient active and inactive). These sources of information will include but not be limited to Poison Control Sites, CDC, and all governmental information, both state and federal.